WB,IHC-P,ICC/IF

Peptide sequence around Tri-Methylation site of lysine 27(A-R-K(tri-methyl)-S-A) derived from Human Histone H3.

WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

1 mg/ml

H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

H3C1

H3.3A;HIST1 cluster;H3E;H3 histone family;member A;H3.1;H3/l;H3F3;H3FF;H3FJ;H3FL;Histone gene cluster 1;member E;histone H3.1t;Histone H3/o;FLJ92264;H 3;H3;member B;member C;member D;member F;member H;member I;member J;member K;member L;member T;H3 histone;family 3A;H3/A;H3/b;H3/c;H3/d;h3/f;H3/h;H3/i;H3/j;H3/k;H3/t;H31_HUMAN;H3F1K;H3F3A;H3FA;H3FB;H3FC;H3FD;H3FH;H3FI;H3FK;H3A;H3B;H3C;H3D;H3F;H3G;H3H;H3I;H3J;HIST1H3A;HIST1H3B;HIST1H3C;HIST1H3D;HIST1H3E;HIST1H3F;HIST1H3G;HIST1H3H;HIST1H3I;HIST1H3J;HIST3H3;Histone 1;Histone 3;histone cluster 1 H3 family member a;histone cluster 1 H3 family member b;histone cluster 1 H3 family member c;histone cluster 1 H3 family member d;histone cluster 1 H3 family member e;histone cluster 1 H3 family member f;histone cluster 1 H3 family member g;histone cluster 1 H3 family member h;histone cluster 1 H3 family member i;histone cluster 1 H3 family member j;Histone cluster 1;member G;Histone H 3;Histone H3.1;Histone H3.2;Histone H3.3;Histone H3/a;Histone H3/b;Histone H3/c;Histone H3/d;Histone H3/f;Histone H3/h;Histone H3/i;Histone H3/j;Histone H3/k;Histone H3/l;Histone H3/m;H3C1;H3K27me3

SwissProt ID P68431

Gene ID 8350

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.