免疫原
Synthesized peptide derived from human OSBL1 AA range: 229-279
特异性
This antibody detects endogenous levels of OSBL1 at Human/Mouse/Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.209% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms. [provided by RefSeq, Jul 2008],
功能
function:Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate.,similarity:Belongs to the OSBP family.,similarity:Contains 1 PH domain.,similarity:Contains 3 ANK repeats.,subunit:Interacts with VAPA.,
基因名称（Gene Name）
OSBPL1A ORP1 OSBP8 OSBPL1 OSBPL1B
其他名称
FLJ1217;ORP 1;ORP-1;ORP1;OSBL1_HUMAN;OSBP 8;OSBP L1;OSBP related protein 1;OSBP-related protein 1;OSBP8;OSBPL 1;OSBPL 1A;OSBPL 1B;OSBPL1;OSBPL1A;OSBPL1B;Oxysterol binding protein like 1A;Oxysterol binding protein like 1B;Oxysterol binding protein related protein 1;Oxysterol-binding protein-related protein 1;OSBL1;OSBPL1A ORP1 OSBP8 OSBPL1 OSBPL1B;Oxysterol-binding protein-related protein 1 (ORP-1) (OSBP-related protein 1)
细胞定位
Late endosome . Colocalizes with RAB7A, RAB9A and LAMP1 in late endosomes.
组织表达
Bone,Brain,Embryo,Epithelium,Kidney,Pancreas,Testicle,
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