免疫原
Synthesized peptide derived from human IFT140
特异性
This antibody detects endogenous levels of IFT140 at Human
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs) . Plays a pivotal role in proper development and function of ciliated cells through its role in ciliogenesis and/or cilium maintenance . Required for the development and maintenance of the outer segments of rod and cone photoreceptor cells. Plays a role in maintenance and the delivery of opsin to the outer segment of photoreceptor cells (By similarity).
基因名称(Gene Name)
IFT140 KIAA0590 WDTC2
蛋白名称
Intraflagellar transport protein 140 homolog (WD and tetratricopeptide repeats protein 2)
其他名称
Intraflagellar transport protein 140 homolog;KIAA0590;WDTC2;IFT140 KIAA0590 WDTC2;Intraflagellar transport protein 140 homolog (WD and tetratricopeptide repeats protein 2)
细胞定位
Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cell projection, cilium .
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)