免疫原
The antiserum was produced against synthesized peptide derived from human KIF20A around the phosphorylation site of Ser528. AA range:501-550
特异性
Phospho-KIF20A (S528) Polyclonal Antibody detects endogenous levels of KIF20A protein only when phosphorylated at S528.
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/5000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
function:Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.,similarity:Belongs to the kinesin-like protein family.,similarity:Contains 1 kinesin-motor domain.,
功能
function:Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.,similarity:Belongs to the kinesin-like protein family.,similarity:Contains 1 kinesin-motor domain.,
蛋白名称
Kinesin-like protein KIF20A
其他名称
AA415432;FLJ21151;GG1 2;GG1_2;KI2A_HUMAN;KIF2A;kinesin family member 2A;Kinesin like protein KIF2A;Kinesin-like protein 174;Kinesin-like protein KIF2A;mitotic kinesin like protein 2;Mitotic kinesin-like protein 2;MKlp2;OTTHUMP159481;RAB6 interacting;kinesin like (rabkinesin6);Rab6-interacting kinesin-like protein;RAB6-INTERACTING PROTEIN;KINESIN-LIKE;RAB6KIFL;Rabkinesin 6;Rabkinesin-6;KIF20A;Kinesin-like protein KIF20A;GG10_2
细胞定位
Golgi apparatus . Cytoplasm, cytoskeleton, spindle . Localizes to the spindle midzone during anaphase and telophase. .
组织表达
Brain,Endothelial cell,Epithelium,Uterus,