免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human STRA8. AA range:151-200
特异性
Stra8 Monoclonal Antibody detects endogenous levels of Stra8 protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a retinoic acid-responsive protein. A homologous protein in mouse has been shown to be involved in the regulation of meiotic initiation in both spermatogenesis and oogenesis, though feature differences between the mouse and human proteins suggest that these homologs are not entirely functionally equivalent. It is thought that this gene may play a role in spermatogenesis in humans. [provided by RefSeq, Nov 2010],
功能
function:Required for the transition into meiosis for both female and male germ cells. In female germ cells, required for premeiotic DNA replication and subsequent events in meiotic prophase.,PTM:Phosphorylated.,tissue specificity:Expressed specifically in testis.,
蛋白名称
Stimulated by retinoic acid gene 8 protein homolog
其他名称
STRA8; Stimulated by retinoic acid gene 8 protein homolog
细胞定位
Cytoplasm . Nucleus . Shuttles between nucleus and cytoplasm. Nuclear export is XPO1-dependent. .
组织表达
Expressed specifically in testis and fetal ovaries.