背景（Background）
function:Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.,similarity:Contains 3 UPAR/Ly6 domains.,subunit:Monomer (Probable). Interacts with MRC2.,
功能
protein amino acid lipidation, GPI anchor metabolic process, GPI anchor biosynthetic process, phospholipid metabolic process, glycerophospholipid metabolic process, cell motion, chemotaxis, blood coagulation, hemostasis, behavior,locomotory behavior, lipid biosynthetic process, phospholipid biosynthetic process, response to wounding, attachment of GPI anchor to protein, organophosphate metabolic process, regulation of proteolysis, phosphoinositide metabolic process, regeneration, growth, wound healing, lipoprotein metabolic process, lipoprotein biosynthetic process, tissue regeneration, taxis, skeletal muscle regeneration, glycerolipid biosynthetic process, glycerophospholipid biosynthetic process, glycerolipid metabolic process, phosphoinositide biosynthetic process, developmental growth, coagulation,regulation of body fluid levels,
细胞定位
Cell membrane . Cell projection, invadopodium membrane . Colocalized with FAP (seprase) preferentially at the cell surface of invadopodia membrane in a cytoskeleton-, integrin- and vitronectin-dependent manner. .; [Isoform 1]: Cell membrane ; Lipid-anchor, GPI-anchor .; [Isoform 2]: Secreted .
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