免疫原
Synthesized peptide derived from human DRG1. AA range:127-227
特异性
This antibody detects endogenous levels of DRG1 at Human, Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP . Appears to have an intrinsic GTPase activity that is stimulated by ZC3H15/DFRP1 binding likely by increasing the affinity for the potassium ions . When hydroxylated at C-3 of 'Lys-22' by JMJD7 , may bind to RNA and play a role in translation . Binds to microtubules and promotes microtubule polymerization and stability that are required for mitotic spindle assembly during prophase to anaphase transition. GTPase activity is not necessary for these microtubule-related functions .
基因名称（Gene Name）
DRG1 NEDD3
蛋白名称
Developmentally-regulated GTP-binding protein 1 (DRG-1) (Neural precursor cell expressed developmentally down-regulated protein 3) (NEDD-3)
其他名称
=_xlfn.TEXTJOIN(";",TRUE,W3216,X3216,Y3216,Z3216)
细胞定位
Nucleus . Cytoplasm . The DRG1-ZC3H15/DFRP1 complex associates with polysomes.
组织表达
High levels in skeletal muscle , heart , and kidney. Intermediate levels in liver , placenta and brain. Low levels in colon , thymus , spleen , small intestine , lung and leukocytes.
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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