WB

Synthesized peptide derived from human COX7C

This antibody detects endogenous levels of COX7C at Human, Mouse,Rat

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

WB 1:500-2000

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.

COX7C

Cytochrome c oxidase subunit 7C;mitochondrial (Cytochrome c oxidase polypeptide VIIc)

Cytochrome c oxidase subunit 7C;mitochondrial;COX7C;mitochondrial (Cytochrome c oxidase polypeptide VIIc)

1350

P15954

100048613

P17665

100188937

P80432

Mitochondrion inner membrane ; Single-pass membrane protein .

-15°C to -25°C/1 year(Do not lower than -25°C)