免疫原
Synthesized peptide derived from human DDHD2
特异性
This antibody detects endogenous levels of DDHD2 at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Phospholipase that hydrolyzes preferentially phosphatidic acid, including 1,2-dioleoyl-sn-phosphatidic acid, and phosphatidylethanolamine. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P), phosphatidylinositol 5-phosphate (PI(5)P) and possibly phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2). May be involved in the maintenance of the endoplasmic reticulum and/or Golgi structures. May regulate the transport between Golgi apparatus and plasma membrane.
基因名称(Gene Name)
DDHD2 KIAA0725 SAMWD1
蛋白名称
Phospholipase DDHD2 (DDHD domain-containing protein 2) (SAM;WWE and DDHD domain-containing protein 1)
其他名称
DDHD domain containing 2;DDHD2;KIAA0725;KIAA0725p;Phospholipase DDHD2;SAMWD1;DDHD2 KIAA0725 SAMWD1;Phospholipase DDHD2 (DDHD domain-containing protein 2) (SAM;WWE and DDHD domain-containing protein 1)
细胞定位
Cytoplasm, cytosol. Endoplasmic reticulum-Golgi intermediate compartment. Golgi apparatus, cis-Golgi network. Cycles between the Golgi apparatus and the cytosol. DDHD2 recruitment to the Golgi/endoplasmic reticulum-Golgi intermediate compartment (ERGIC) is regulated by the levels of phosphoinositides, including PI(4)P.
组织表达
Widely expressed (at protein level).
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)