免疫原
Synthesized peptide derived from human CCDC40
特异性
This antibody detects endogenous levels of CCDC40 at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella . Probably acts together with CCDC39 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (By similarity). Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39 .
基因名称(Gene Name)
CCDC40 KIAA1640
蛋白名称
Coiled-coil domain-containing protein 40
其他名称
KIAA1640;Coiled-coil domain-containing protein 40;CCDC40 KIAA1640
细胞定位
Cytoplasm . Cell projection, cilium . Localizes to cytoplasm and motile cilium. .
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)