免疫原
Synthesized peptide derived from human FBXL15
特异性
This antibody detects endogenous levels of FBXL15 at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2.
基因名称(Gene Name)
FBXL15 FBXO37
蛋白名称
F-box/LRR-repeat protein 15 (F-box only protein 37)
其他名称
F box only protein 37;F box/LRR repeat protein 15;Fbl15;FBXL15;FBXO37;JET;PSD;FBXL15 FBXO37;F-box/LRR-repeat protein 15 (F-box only protein 37)
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)