免疫原
The antiserum was produced against synthesized peptide derived from human CDC2L1. AA range:10-59
特异性
PITSLRE Polyclonal Antibody detects endogenous levels of PITSLRE protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014],
功能
caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,
蛋白名称
Cyclin-dependent kinase 11B
其他名称
CD11A_HUMAN;CDC2L2;CDC2L3;CDK11;CDK11 p11;CDK11 p46;CDK11 p58;CDK11A;Cell division cycle 2 like 2 (PITSLRE proteins);Cell division cycle 2-like protein kinase 2;Cell division protein kinase 11A;Cyclin-dependent kinase 11A;Galactosyltransferase-associated protein kinase p58/GTA;p58GTA;PITSLRE;PITSLRE B;PITSLRE protein kinase beta;PITSLRE serine/threonine-protein kinase CDC2L2;PITSLREB;CDC2L1;Cell division cycle 2-like protein kinase 1;Cell division protein kinase 11B;CLK 1;EC=2.7.11.22;Galactosyltransferase associated protein kinase p58/GTA;ITSLRE serine/threonine protein kinase CDC2L1;p58 CLK 1;PITSLREA;PK58;CDK11B;Cyclin-dependent kinase 11B;CLK-1;PITSLRE serine/threonine-prot
组织表达
Expressed ubiquitously. Some evidence of isoform-specific tissue distribution.