免疫原
Synthesized peptide derived from human ARL4C
特异性
This antibody detects endogenous levels of ARL4C at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. May be involved in transport between a perinuclear compartment and the plasma membrane, apparently linked to the ABCA1-mediated cholesterol secretion pathway. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in the GDP-bound form. Regulates the microtubule-dependent intracellular vesicular transport from early endosome to recycling endosome process.
基因名称(Gene Name)
ARL4C ARL7
蛋白名称
ADP-ribosylation factor-like protein 4C (ADP-ribosylation factor-like protein 7) (ADP-ribosylation factor-like protein LAK)
其他名称
ADP ribosylation factor like 4C;ADP ribosylation factor like 7;ADP-ribosylation factor-like protein 4C;ADP-ribosylation factor-like protein 7;ADP-ribosylation factor-like protein LAK;Arl4c;ARL4C_HUMAN;ARL7;LAK;ARL4C ARL7;ADP-ribosylation factor-like protein 4C (ADP-ribosylation factor-like protein 7) (ADP-ribosylation factor-like protein LAK)
细胞定位
Cell projection, filopodium. Cell membrane. Cytoplasm.
组织表达
Expressed in several tumor cell lines (at protein level). Expressed in lung, brain, leukocytes and placenta.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)