免疫原
Synthesized peptide derived from human CTMP
特异性
This antibody detects endogenous levels of CTMP at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and probably plays a role in mitochondrial fatty acid metabolism. Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity. According to PubMed:11598301, inhibits AKT1 phosphorylation and activity. According to PubMed:17615157, enhances AKT1 activity by favoring its phosphorylation and translocation to plasma membrane.
基因名称（Gene Name）
THEM4 CTMP
蛋白名称
Thioesterase superfamily member 4 (Carboxyl-terminal modulator protein)
其他名称
THEM4;EC:3.1.2.2;Carboxyl-terminal modulator protein;Acyl-coenzyme A thioesterase THEM4;Acyl-CoA thioesterase THEM4;THEM4 CTMP;Thioesterase superfamily member 4 (Carboxyl-terminal modulator protein)
细胞定位
Cell membrane . Cell projection, ruffle membrane . Cytoplasm . Mitochondrion . Mitochondrion inner membrane; Peripheral membrane protein . Mitochondrion intermembrane space . Released from the mitochondria into the cytosol in response to apoptotic stimuli. .
组织表达
Expressed predominantly in skeletal muscle, testis, uterus, brain and kidney. Down-regulated in glioblastoma or glioma compared to non-neoplastic brain due to promoter hypermethylation.
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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