免疫原
Synthesized peptide derived from human MUS81
特异性
This antibody detects endogenous levels of MUS81 at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. Plays an essential role in mitosis for the processing of stalled or collapsed replication forks .
蛋白名称
Crossover junction endonuclease MUS81 (EC 3.1.22.-)
其他名称
SLX3;MUS81;Crossover junction endonuclease MUS81 (EC 3.1.22.-)
细胞定位
Nucleus, nucleolus . Recruited to foci of DNA damage in S-phase cells.
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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