免疫原
Synthesized peptide derived from human TWEAKR/FN14
特异性
This antibody detects endogenous levels of TWEAKR/FN14 at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
基因名称(Gene Name)
TNFRSF12A FN14
蛋白名称
Tumor necrosis factor receptor superfamily member 12A (Fibroblast growth factor-inducible immediate-early response protein 14) (FGF-inducible 14) (Tweak-receptor) (TweakR) (CD antigen CD266)
其他名称
FN14;CD266;TWEAKR;TWEAKR/Fn14/CD266;TNFRSF12A FN14;Tumor necrosis factor receptor superfamily member 12A (Fibroblast growth factor-inducible immediate-early response protein 14) (FGF-inducible 14) (Tweak-receptor) (TweakR) (CD antigen CD266)
细胞定位
Membrane; Single-pass type I membrane protein.
组织表达
Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)