免疫原
The antiserum was produced against synthesized peptide derived from human RHBT2. AA range:61-110
特异性
RhoBTB1/2 Polyclonal Antibody detects endogenous levels of RhoBTB1/2 protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008],
功能
similarity:Belongs to the small GTPase superfamily. Rho family.,similarity:Contains 2 BTB (POZ) domains.,tissue specificity:Ubiquitous, with highest levels in skeletal muscle, placenta, testis, stomach, and kidney, followed by uterus and adrenal gland. Expressed in a variety of fetal tissues.,
基因名称（Gene Name）
RHOBTB1/RHOBTB2
蛋白名称
Rho-related BTB domain-containing protein 1/2
其他名称
DBC 2;Deleted in breast cancer 2;Deleted in breast cancer 2 gene protein;p83;RHBT2_HUMAN;Rho related BTB domain containing 2;Rho related BTB domain containing protein 2;Rho-related BTB domain-containing protein 2;RHOBTB 2;Rhobtb2;178H16Rik;31148G13Rik;AI173445;AI573858;AV3593;KIAA74;MGC17538;MGC3359;MGC33841;OTTHUMP19662;OTTHUMP19663;RHBT1_HUMAN;Rho related BTB domain containing 1;Rho related BTB domain containing protein 1;Rho-related BTB domain-containing protein 1;Rhobtb1;RhoBTB1/2;RHOBTB1/RHOBTB2;Rho-related BTB domain-containing protein 1/2;KIAA0740;DBC2;KIAA0717
Fields
>>Ubiquitin mediated proteolysis
细胞定位
intracellular,cytosol,plasma membrane,
组织表达
Ubiquitous, with highest levels in skeletal muscle, placenta, testis, stomach, and kidney, followed by uterus and adrenal gland. Expressed in a variety of fetal tissues.
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