免疫原
Synthesized peptide derived from human CIP2A
特异性
This antibody detects endogenous levels of CIP2A at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Oncoprotein that inhibits PP2A and stabilizes MYC in human malignancies. Promotes anchorage-independent cell growth and tumor formation.
基因名称(Gene Name)
KIAA1524 CIP2A
蛋白名称
Protein CIP2A (Cancerous inhibitor of PP2A) (p90 autoantigen)
其他名称
KIAA1524;Cancerous inhibitor of PP2A;p90;p90 autoantigen;Protein CIP2A;KIAA1524 CIP2A;Protein CIP2A (Cancerous inhibitor of PP2A) (p90 autoantigen)
细胞定位
Membrane ; Single-pass membrane protein . Cytoplasm . Slightly concentrates in the perinuclear region (PubMed:12118381). .
组织表达
Expressed at low levels in most of the tissues. Overexpressed in head-and-neck squamous cell carcinomas (HNSCC). Present in liver cancer cells (at protein level).
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)