免疫原
Synthesized peptide derived from human PES1
特异性
This antibody detects endogenous levels of PES1 at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
其他名称
FLJ4379;Homo sapiens pescadillo mRNA complete cds;PES;PES 1;pes1;PESC_HUMAN;Pescadillo (zebrafish) homolog 1 containing BRCT domain;Pescadillo homolog 1;Pescadillo homolog 1 containing BRCT domain (zebrafish);Pescadillo homolog;Pescadillo ribosomal biogenesis factor 1
细胞定位
Nucleus, nucleolus. Nucleus, nucleoplasm. Chromosome. Appears to localize to the periphery of metaphase chromosomes during mitosis and to the prenucleolar bodies that form in mitotic cells prior to the actual nucleoli. .
组织表达
Significant levels are detected in a variety of cancer cell lines, including glioblastoma, breast carcinoma, colon carcinoma and cervical carcinoma cells. Levels are abnormally elevated in malignant tumors of astrocytic origin.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)