免疫原
Synthesized peptide derived from human FBP1
特异性
This antibody detects endogenous levels of FBP1 at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
蛋白名称
Fructose-1;6-bisphosphatase 1 (FBPase 1) (EC 3.1.3.11) (D-fructose-1;6-bisphosphate 1-phosphohydrolase 1)
其他名称
D-fructose-1;6-bisphosphate 1-phosphohydrolase 1;EC:3.1.3.11;FBP;FBPase 1;Fructose-1;6-bisphosphatase 1;FBP1;FBP1 FBP;6-bisphosphatase 1 (FBPase 1) (EC 3.1.3.11) (D-fructose-1;6-bisphosphate 1-phosphohydrolase 1)
细胞定位
Expressed in pancreatic islets.
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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