免疫原
Synthesized peptide derived from human CPLX3
特异性
This antibody detects endogenous levels of CPLX3 at Human, Mouse
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion (By similarity). Required for the maintenance of synaptic ultrastructure in the adult retina (By similarity). Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina (By similarity). Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca(2+) vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca(2+) vesicle release (By similarity).
基因名称(Gene Name)
CPLX3 Nbla11589
蛋白名称
Complexin-3 (Complexin III) (CPX III)
其他名称
complexin 3;Complexin III;Complexin-3;CPX III;CPXIII;CPLX3 Nbla11589;Complexin-3 (Complexin III) (CPX III)
细胞定位
Cell junction, synapse . Cell membrane; Lipid-anchor . Enriched at the synaptic terminal (By similarity). Localized at glycinergic synaptic contacts of AII amacrine cells with OFF cone bipolar cells in the OFF sublamina of the retina inner nuclear layer (By similarity). .
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)