免疫原
A synthetic peptide of human SIRT3
稀释比例
WB: 1/500-1/1000 IHC: 1/50-1/100
背景(Background)
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.
其他名称
EC:2.3.1.286;hSIRT3;NAD-dependent protein deacetylase sirtuin-3;mitochondrial;Regulatory protein SIR2 homolog 3;SIR2 like protein 3;SIRT3;SIR2L3
人基因ID
SwissProt ID
Q9NTG7
储存(Storage)
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.