免疫原
Synthesized peptide derived from human CX7A1 AA range: 1-50
特异性
This antibody detects endogenous levels of CX7A1 at Human/Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
IHC-p 1：50-200. IF 1:50-200
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景（Background）
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (muscle isoform) of subunit VIIa and the polypeptide 1 is present only in muscle tissues. Other polypeptides of subunit VIIa are present in both muscle and nonmuscle tissues, and are encoded by different genes. [provided by RefSeq, Jul 2008],
功能
function:This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.,similarity:Belongs to the cytochrome c oxidase VIIa family.,
基因名称（Gene Name）
COX7A1 COX7AH
其他名称
COX7A;COX7A1;COX7AH;COX7AM;CX7A1_HUMAN;Cytochrome c oxidase subunit 7A1;Cytochrome c oxidase subunit 7A1 mitochondrial;Cytochrome c oxidase subunit VIIa H;Cytochrome c oxidase subunit VIIa heart;Cytochrome c oxidase subunit VIIa heart/muscle isoform;Cytochrome c oxidase subunit VIIa M;Cytochrome c oxidase subunit VIIa muscle;Cytochrome c oxidase subunit VIIa polypeptide 1 (muscle);Cytochrome c oxidase subunit VIIa polypeptide 1;Cytochrome c oxidase subunit VIIa-H;Cytochrome c oxidase subunit VIIa-heart;Cytochrome c oxidase subunit VIIa-M;Cytochrome c oxidase subunit VIIa-muscle;mitochondrial;CX7A1;COX7A1 COX7AH
Fields
>>Oxidative phosphorylation;>>Metabolic pathways;>>Cardiac muscle contraction;>>Thermogenesis;>>Non-alcoholic fatty liver disease;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Chemical carcinogenesis - reactive oxygen species;>>Diabetic cardiomyopathy
细胞定位
Mitochondrion inner membrane ; Single-pass membrane protein .
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