免疫原
Synthesized peptide derived from human RBM15B
特异性
This antibody detects endogenous levels of RBM15B at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
RNA-binding protein that acts as a key regulator of N6-methyladenosine (m6A) methylation of RNAs, thereby regulating different processes, such as alternative splicing of mRNAs and X chromosome inactivation mediated by Xist RNA . Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing . Plays a key role in m6A methylation, possibly by binding target RNAs and recruiting the WMM complex . Involved in random X inactivation mediated by Xist RNA: acts by binding Xist RNA and recruiting the WMM complex, which mediates m6A methylation, leading to target YTHDC1 reader on Xist RNA and promoting transcription repression activity of Xist . Functions in the regulation of alternative or illicit splicing, possibly by regulating m6A methylation . Inhibits pre-mRNA splicing . Also functions as a mRNA export factor by acting as a cofactor for the nuclear export receptor NXF1 .
基因名称（Gene Name）
RBM15B OTT3
蛋白名称
Putative RNA-binding protein 15B (One-twenty two protein 3) (HuOTT3) (RNA-binding motif protein 15B)
其他名称
OTT3;HsOTT3;HUMAGCGB;RBM15B;RBM15B OTT3;Putative RNA-binding protein 15B (One-twenty two protein 3) (HuOTT3) (RNA-binding motif protein 15B)
细胞定位
Nucleus, nucleoplasm . Nucleus speckle . Nucleus envelope . Colocalizes with BMLF1 in the nucleus. Localized in the nucleoplasm with a granular staining pattern and excluded from the nucleoli. .
组织表达
Ubiquitously expressed.
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
联系我们
关注我们
您当前的位置： 
成功添加到购物车
