免疫原
Synthesized peptide derived from human HOOK1 AA range: 201-251
特异性
This antibody detects endogenous levels of human HOOK1
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
蛋白名称
Protein Hook homolog 1 (h-hook1) (hHK1)
其他名称
Protein Hook homolog 1;hook homolog 1 (Drosophila);HK1;h-hook1;hHK1;HOOK1;Protein Hook homolog 1 (h-hook1) (hHK1)
细胞定位
Cytoplasm . Cytoplasm, cytoskeleton . Localizes to punctate cytoplasmic foci which do not appear to overlap with early or late endosomes, the endoplasmic reticulum, multivesicular bodies (MVBs), lysosomes, or mitochondria (By similarity). Often found in close association with microtubules (By similarity). Does not associate with the Golgi complex. During spermiogenesis, it localizes to the manchette in spermatids from steps 8-10. It is also present between the microtubule manchette and the nucleus. During manchette elongation, it is preferentially localized to the nuclear ring of the manchette, whereas the strong localization to the manchette decreases. In more mature spermatids, while the manchette migrates posteriorly, it localizes to punctuates spots. At later stages of spermatid differ