免疫原
Synthesized peptide derived from human CLPP
特异性
This antibody detects endogenous levels of CLPP at Human, Mouse
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The Clp complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates . Cleaves PINK1 in the mitochondrion .
蛋白名称
Putative ATP-dependent Clp protease proteolytic subunit;mitochondrial (Endopeptidase Clp)
其他名称
DFNB81;PRLTS3;CLPP;Putative ATP-dependent Clp protease proteolytic subunit;mitochondrial (Endopeptidase Clp)
细胞定位
Mitochondrion matrix .
组织表达
Detected in liver (at protein level). Predominantly expressed in skeletal muscle. Intermediate levels in heart, liver and pancreas. Low in brain, placenta, lung and kidney.
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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