免疫原
Synthesized peptide derived from human SSRB AA range: 107-157
特异性
This antibody detects endogenous levels of SSRB at Human/Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
背景(Background)
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23. [provided by RefSeq, Jul 2008],
功能
function:TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.,similarity:Belongs to the TRAP-beta family.,subunit:Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma. Interacts with TMEM173/STING.,
基因名称(Gene Name)
SSR2 TRAPB HSD25
其他名称
Beta SSR;DKFZp686F19123;HSD25;Signal sequence receptor subunit beta;Signal sequence receptor;beta;beta (translocon associated protein beta);SRIF 1;SS2R;SSR 2;SSR beta;SSR-beta;ssr2;SSRB;SSRB_HUMAN;TLAP;Translocon associated protein beta;Translocon-associated protein subunit beta;TRAP BETA;TRAP-beta;TRAPB;SSR2 TRAPB HSD25
Fields
>>Protein processing in endoplasmic reticulum
细胞定位
Endoplasmic reticulum membrane; Single-pass type I membrane protein.