免疫原
Synthesized peptide derived from human RAB27B
特异性
This antibody detects endogenous levels of RAB27B at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion . Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1 . May be involved in targeting uroplakins to urothelial apical membranes (By similarity).
蛋白名称
Ras-related protein Rab-27B (C25KG)
其他名称
C25KG;RAB27B;Ras-related protein Rab-27B (C25KG)
细胞定位
Membrane; Lipid-anchor. Late endosome .
组织表达
Expressed primarily in testis.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)