免疫原
Purified recombinant H-FABP protein expressed in E.coli
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
背景（Background）
The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
功能
domain:Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.,function:FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,
其他名称
H-FABP;fabp3;422 protein;Cardiac Fatty Acid Binding Protein;FABP 11;FABP 3;FABP11;FABPH_HUMAN;fatty acid binding protein 11;Fatty acid binding protein 3;Fatty acid binding protein 3 muscle and heart;Fatty acid binding protein 3 muscle and heart mammary derived growth inhibitor;Fatty acid binding protein 3 muscle;muscle and heart (mammary derived growth inhibitor);muscle;Fatty acid binding protein heart;Fatty acid binding protein;heart;muscle and heart;skeletal muscle;Fatty acid-binding protein 3;Fatty acid-binding protein;H FABP;Heart type fatty acid binding protein;Heart-type fatty acid-binding protein;M FABP;M-FABP;mammary derived growth inhibitor;Mammary-derived growth inhibitor;MDGI;Muscle fatty acid binding protein;Muscle fatty acid-binding protein;mylein protein P2 homolog;O FABP;OTTHUMP00000003898;P2 adopocyte protein.
Fields
>>PPAR signaling pathway
组织表达
Fetal brain cortex,Heart,Liver,Mammary gland,Skeletal muscle,
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