免疫原
Recombinant Protein of β-tubulin (HRP Conjugated)
特异性
Theβ-tubulin antibody can detects endogenousβ-tubulin protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
稀释比例
WB: 1:1000-1:3000,IHC: 1:50-1:200 IF 1:200
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a beta tubulin protein. This protein forms a dimer with alpha tubulin and acts as a structural component of microtubules. Mutations in this gene cause cortical dysplasia, complex, with other brain malformations 6. Alternative splicing results in multiple splice variants. There are multiple pseudogenes for this gene on chromosomes 1, 6, 7, 8, 9, and 13. [provided by RefSeq, Jun 2014],
功能
domain:The highly acidic C-terminal region may bind cations such as calcium.,function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.,online information:Tubulin entry,similarity:Belongs to the tubulin family.,subunit:Dimer of alpha and beta chains.,tissue specificity:Ubiquitously expressed with highest levels in spleen, thymus and immature brain.,
蛋白名称
Tubulin beta chain (Tubulin beta-5 chain)
其他名称
Tubulin beta 3 chain;Tubulin beta III;β III tubulin;βIII tubulin;TUBB4;Tubulin β;TUBB;Tubulin beta chain (Tubulin beta-5 chain)
Fields
>>Phagosome;>>Gap junction;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Pathogenic Escherichia coli infection;>>Salmonella infection
细胞定位
Cytoplasm, cytoskeleton .
组织表达
Ubiquitously expressed with highest levels in spleen, thymus and immature brain.
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