免疫原
Synthesized peptide derived from human protein . at AA range: 60-140
特异性
PAIRB Polyclonal Antibody detects endogenous levels of protein.
来源
Polyclonal, Rabbit,IgG
组成(Formulation)
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
稀释比例
WB 1:500-2000 ELISA 1:5000-20000
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
function:May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay.,subcellular location:Also found in perinuclear regions.,subunit:Interacts with CHD3 and TDRD3.,tissue specificity:Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain.,
功能
function:May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay.,subcellular location:Also found in perinuclear regions.,subunit:Interacts with CHD3 and TDRD3.,tissue specificity:Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain.,
基因名称(Gene Name)
SERBP1 PAIRBP1 CGI-55
蛋白名称
Plasminogen activator inhibitor 1 RNA-binding protein (PAI1 RNA-binding protein 1) (PAI-RBP1) (SERPINE1 mRNA-binding protein 1)
细胞定位
Cytoplasm . Nucleus . Cytoplasm, perinuclear region .
组织表达
Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain.