免疫原
Synthesized peptide derived from human FAM
特异性
This antibody detects endogenous levels of FAM168B at Human, Mous
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02
纯化工艺(Immunogen)
Synthesized peptide derived from human FA
功能
Inhibitor of neuronal axonal outgrowth. Acts as a negative regulator of CDC42 and STAT3 and a positive regulator of STMN2. Positive regulator of CDC
基因名称(Gene Name)
FAM168B KIAA0280L MA
蛋白名称
Myelin-associated neurite-outgrowth inhibitor (Mani) (p
细胞定位
Cytoplasm, perinuclear region . Cell membrane ; Multi-pass membrane protein . Cell projection, axon . Expressed in neuronal cell bodies and a
组织表达
Expressed in the brain, within neuronal axonal fibers and associated with myelin sheets (at protein level). Expression tends to be lower in the brain of Alzheimer disease patients compared to healthy individuals (at protein lev