免疫原
Synthesized peptide derived from human ESCO2
特异性
This antibody detects endogenous levels of ESCO2 at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Acetyltransferase required for the establishment of sister chromatid cohesion . Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during the S phase. Acetylates the cohesin component SMC3 .
蛋白名称
N-acetyltransferase ESCO2 (EC 2.3.1.-) (Establishment of cohesion 1 homolog 2) (ECO1 homolog 2)
细胞定位
Nucleus . Chromosome . Nuclear in interphase cells, excluded from chromosomes during metaphase but reassociates with chromosomes in telophase. .
组织表达
Widely expressed in fetal tissues. In adult, it is expressed in thymus, placenta and small intestine.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)