免疫原
Synthesized peptide derived from human SUMF1
特异性
This antibody detects endogenous levels of SUMF1 at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Oxidase that catalyzes the conversion of cysteine to 3-oxoalanine on target proteins, using molecular oxygen and an unidentified reducing agent . 3-oxoalanine modification, which is also named formylglycine (fGly), occurs in the maturation of arylsulfatases and some alkaline phosphatases that use the hydrated form of 3-oxoalanine as a catalytic nucleophile . Known substrates include GALNS, ARSA, STS and ARSE .
基因名称(Gene Name)
SUMF1 FGE PSEC0152 UNQ3037/PRO9852
蛋白名称
Sulfatase-modifying factor 1 (EC 1.8.99.-) (C-alpha-formylglycine-generating enzyme 1)
细胞定位
Endoplasmic reticulum lumen .
组织表达
Ubiquitous. Highly expressed in kidney, pancreas and liver. Detected at lower levels in leukocytes, lung, placenta, small intestine, skeletal muscle and heart.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)