免疫原
Synthesized peptide derived from human XPNPEP3
特异性
This antibody detects endogenous levels of XPNPEP3 at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Leu-Pro-Ala . Also shows low activity towards peptides with Ala or Ser at the P1 position . ; [Isoform 1]: Promotes TNFRSF1B-mediated phosphorylation of MAPK8/JNK1 and MAPK9/JNK2, suggesting a function as an adapter protein for TNFRSF1B; the effect is independent of XPNPEP3 peptidase activity. May inhibit apoptotic cell death induced via TNF-TNFRSF1B signaling.
蛋白名称
Probable Xaa-Pro aminopeptidase 3 (X-Pro aminopeptidase 3) (EC 3.4.11.9) (Aminopeptidase P3) (APP3)
细胞定位
[Isoform 1]: Mitochondrion . Cytoplasm . Mainly mitochondrial. Translocates to the cytoplasm following TNFRSF1B activation. .; [Isoform 2]: Cytoplasm .
组织表达
Isoform 1 and isoform 2 are widely expressed, with isoform 1 being more abundant.
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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