免疫原
Synthesized peptide derived from human Nesprin 4
特异性
This antibody detects endogenous levels of Nesprin 4 at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
功能
As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning (By similarity). Behaves as a kinesin cargo, providing a functional binding site for kinesin-1 at the nuclear envelope. Hence may contribute to the establishment of secretory epithelial morphology by promoting kinesin-dependent apical migration of the centrosome and Golgi apparatus and basal localization of the nucleus (By similarity).
基因名称（Gene Name）
SYNE4 C19orf46
蛋白名称
Nesprin-4 (Nuclear envelope spectrin repeat protein 4)
细胞定位
Nucleus outer membrane ; Single-pass type IV membrane protein . Localization at the nucleus outer membrane requires the presence of SUN1. .
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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