免疫原
Synthesized peptide derived from human RGS2
特异性
This antibody detects endogenous levels of RGS2 at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form . It is involved in the negative regulation of the angiotensin-activated signaling pathway . Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle (By similarity). Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein .
基因名称（Gene Name）
RGS2 G0S8 GIG31
蛋白名称
Regulator of G-protein signaling 2 (RGS2) (Cell growth-inhibiting gene 31 protein) (G0/G1 switch regulatory protein 8)
细胞定位
[Isoform 1]: Cell membrane . Cytoplasm . Nucleus, nucleolus .; [Isoform 2]: Cell membrane . Cytoplasm . Nucleus, nucleolus .; [Isoform 3]: Cell membrane . Cytoplasm . Nucleus, nucleolus .; [Isoform 4]: Cell membrane . Mitochondrion .
组织表达
Expressed in acute myelogenous leukemia (AML) and in acute lymphoblastic leukemia (ALL).
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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