免疫原
The antiserum was produced against synthesized peptide derived from the Internal region of human P2RX3. AA range:81-130
特异性
P2X3 Monoclonal Antibody detects endogenous levels of P2X3 protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage. [provided by RefSeq, Jul 2008],
功能
function:Receptor for ATP that acts as a ligand gated ion channel.,online information:P2X receptor entry,similarity:Belongs to the P2X receptor family.,subunit:Homo- or heteropolymers.,
其他名称
P2RX3; P2X purinoceptor 3; P2X3; ATP receptor; Purinergic receptor
Fields
>>Calcium signaling pathway;>>Neuroactive ligand-receptor interaction;>>Taste transduction
细胞定位
Cell membrane ; Multi-pass membrane protein .
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