免疫原
The antiserum was produced against synthesized peptide derived from human TNAP1. AA range:71-120
特异性
TNF-IP 1 Monoclonal Antibody detects endogenous levels of TNF-IP 1 protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner. [provided by RefSeq, Jul 2008],
功能
function:Enhances the PCNA-dependent DNA polymerase delta activity.,induction:By TNF-alpha, interleukin-1 beta and lipopolysaccharide (LPS).,similarity:Belongs to the KCTD10/KCTD13/TNFAIP1 family.,similarity:Contains 1 BTB (POZ) domain.,subunit:Interacts with PCNA.,
蛋白名称
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
其他名称
TNFAIP1; BACURD2; EDP1; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2; hBACURD2; BTB/POZ domain-containing protein TNFAIP1; Protein B12; Tumor necrosis factor; alpha-induced protein 1, endothelial
细胞定位
Cytoplasm. Nucleus. Endosome. Colocalizes with RHOB in endosomes.
组织表达
Amygdala,Endothelial cell,Epithelium,Lung,