免疫原
Synthetic peptide from human protein at AA range: 101-150
特异性
CD272 Monoclonal Antibody detects endogenous levels of CD272 protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. [provided by RefSeq, Aug 2011],
功能
function:Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response.,PTM:N-glycosylated.,PTM:Phosphorylated on Tyr residues by TNFRSF14 and by antigen receptors cross-linking, both inducing association with PTPN6 and PTPN11.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2. Interacts with TNFRSF14/HVEM.,
蛋白名称
B- and T-lymphocyte attenuator
其他名称
BTLA; B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; CD antigen CD272
细胞定位
Cell membrane ; Single-pass type I membrane protein .
组织表达
PCR rescued clones,Peripheral blood,Thymus,Trachea,
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