免疫原
Synthesized peptide derived from part region of human protein
特异性
SLIK5 Monoclonal Antibody detects endogenous levels of protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
Members of the SLITRK family, such as SLITRK5, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, including SLITRK5, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 [PubMed 14557068]).[supplied by OMIM, Mar 2008],
功能
function:Suppresses neurite outgrowth.,similarity:Belongs to the SLITRK family.,similarity:Contains 16 LRR (leucine-rich) repeats.,tissue specificity:Expressed predominantly in the cerebral cortex of the brain but also at low levels in the spinal cord and medulla.,
基因名称（Gene Name）
SLITRK5 KIAA0918 LRRC11
蛋白名称
SLIT and NTRK-like protein 5 (Leucine-rich repeat-containing protein 11)
Fields
>>Cell adhesion molecules
细胞定位
Membrane ; Single-pass type I membrane protein .
组织表达
Expressed predominantly in the cerebral cortex of the brain but also at low levels in the spinal cord and medulla.
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