免疫原
Synthesized peptide derived from human protein . at AA range: 800-880
特异性
RHG20 Monoclonal Antibody detects endogenous levels of protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
The protein encoded by this gene is an activator of RHO-type GTPases, transducing a signal from RAP1 to RHO and impacting neurite outgrowth. [provided by RefSeq, Sep 2016],
功能
caution:The translocation involving this gene was originally published as t(X;11)(q13;23) (PubMed:15543602), but BRWD3 is localized to Xq21 and not to Xq13.,developmental stage:Low expression is found in fetal liver.,disease:A chromosomal aberration involving ARHGAP20 may be a cause of B-cell chronic lymphocytic leukemia (B-CLL). Translocation t(X;11)(q21;q23) with BRWD3 does not result in fusion transcripts but disrupts both genes.,function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.,similarity:Contains 1 PH domain.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 Rho-GAP domain.,tissue specificity:Expressed predominantly in the brain. Lower expression is found in lymph nodes.,
基因名称（Gene Name）
ARHGAP20 KIAA1391
蛋白名称
Rho GTPase-activating protein 20 (Rho-type GTPase-activating protein 20)
组织表达
Expressed predominantly in the brain. Lower expression is found in lymph nodes.
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