免疫原
Synthesized peptide derived from human protein . at AA range: 180-260
特异性
PLTP Monoclonal Antibody detects endogenous levels of protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
功能
function:Converts HDL into larger and smaller particles. May play a key role in extracellular phospholipid transport and modulation of hdl particles.,similarity:Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.,tissue specificity:Wide tissue distribution. Placenta > pancreas > lung > kidney > heart > liver > skeletal muscle > brain.,
蛋白名称
Phospholipid transfer protein (Lipid transfer protein II)
Fields
>>PPAR signaling pathway;>>Cholesterol metabolism
细胞定位
Secreted . Nucleus . Nuclear export is XPO1/CRM1-dependent. .
组织表达
Widely expressed. Highest level of expression in the ovary, thymus and placenta, with moderate levels found in the pancreas, small intestine, testis, lung and prostrate. Low level expression in the kidney, liver and spleen, with very low levels found in the heart, colon, skeletal muscle, leukocytes and brain. Expressed in the cortical neurons.
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