免疫原
The antiserum was produced against synthesized peptide derived from human ARSI. AA range:311-360
特异性
Arylsulfatase I Monoclonal Antibody detects endogenous levels of Arylsulfatase I protein.
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景（Background）
This gene encodes a protein that belongs to a large family of sulfatases that hydrolyze sulfate esters and sulfamates. Members of this family play a role in several cellular processes, including hormone synthesis, cell signaling in development and degradation of macromolecules. The protein encoded by this gene is thought to be secreted, and to function in extracellular space. [provided by RefSeq, Jul 2016],
功能
cofactor:Binds 1 calcium ion per subunit.,PTM:The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.,similarity:Belongs to the sulfatase family.,
其他名称
ARSI; Arylsulfatase I; ASI
细胞定位
Secreted . Endoplasmic reticulum . Localized in the intracellular granular structures.
组织表达
Expressed in placenta, in embryonic stem cells, fetal eyes and lens.
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