免疫原
The antiserum was produced against synthesized peptide derived from human Tubulin gamma. AA range:386-435
特异性
Tubulin γ Monoclonal Antibody detects endogenous levels of Tubulin γ protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7. [provided by RefSeq, Jan 2009],
功能
function:Tubulin is the major constituent of microtubules. Gamma tubulin is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly.,mass spectrometry: PubMed:11840567,similarity:Belongs to the tubulin family.,subunit:Interacts with GCP2 and GCP3. Interacts with B9D2.,
蛋白名称
Tubulin gamma-1 chain
其他名称
TUBG1; TUBG; Tubulin gamma-1 chain; Gamma-1-tubulin; Gamma-tubulin complex component 1; GCP-1
Fields
>>Human papillomavirus infection
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Localizes to mitotic spindle microtubules. .
组织表达
Mammary cancer,Skin,