免疫原
The antiserum was produced against synthesized peptide derived from human CCS. AA range:225-274
特异性
CCS Monoclonal Antibody detects endogenous levels of CCS protein.
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.
背景(Background)
Copper chaperone for superoxide dismutase specifically delivers Cu to copper/zinc superoxide dismutase and may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor. [provided by RefSeq, Jul 2008],
功能
cofactor:Binds 1 zinc ion per subunit.,cofactor:Binds 2 copper ions per subunit.,function:Delivers copper to copper zinc superoxide dismutase (SOD1).,similarity:Contains 1 HMA domain.,similarity:In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.,subunit:Homodimer, and heterodimer with SOD1.,tissue specificity:Ubiquitous.,
蛋白名称
Copper chaperone for superoxide dismutase
其他名称
CCS; Copper chaperone for superoxide dismutase; Superoxide dismutase copper chaperone
Fields
>>Amyotrophic lateral sclerosis;>>Pathways of neurodegeneration - multiple diseases