免疫原
Synthesized peptide derived from human NUBP2. AA range:86-156
特异性
This antibody detects endogenous levels of NUBP2 at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex , mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Negatively regulates cilium formation and structure.
蛋白名称
Cytosolic Fe-S cluster assembly factor NUBP2 (Nucleotide-binding protein 2) (NBP 2)
其他名称
=_xlfn.TEXTJOIN(";",TRUE,W3227,X3227,Y3227,Z3227)
细胞定位
Nucleus . Cytoplasm , cytoskeleton , microtubule organizing center , centrosome . Cytoplasm . Cytoplasm , cytoskeleton , cilium axoneme . Cytoplasm , cytoskeleton , microtubule organizing center , centrosome , centriole . Cytoplasm , cytoskeleton , microtubule organizing center . Enriched at the centrosomes during mitosis. Enriched in centrioles of microtubule asters during prophase , prometaphase and telophase stages of mitosis (By similarity) . Localized at centrioles and in the nucleus at interphase (By similarity) . Colocalizes with nubp-1 at prometaphase (By similarity) . .
组织表达
Widely expressed with highest expression in skeletal muscle.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)