免疫原
Synthesized peptide derived from human ADHFE1. AA range:202-302
特异性
This antibody detects endogenous levels of ADHFE1 at Human, Mouse,Rat
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG) . D ,L-3-hydroxyisobutyrate and L-3-hydroxybutyrate (L-3-OHB) are also substrates for HOT with 10-fold lower activities.
基因名称(Gene Name)
ADHFE1 HMFT2263
蛋白名称
Hydroxyacid-oxoacid transhydrogenase, mitochondrial (HOT) (Alcohol dehydrogenase iron-containing protein 1) (ADHFe1) (Fe-containing alcohol dehydrogenase)
其他名称
=_xlfn.TEXTJOIN(";",TRUE,W3214,X3214,Y3214,Z3214)
组织表达
Only expressed in adult liver.
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)