免疫原
Synthesized peptide derived from human SH3BP5. AA range:272-372
特异性
This antibody detects endogenous levels of SH3BP5 at Human, Mouse,Rat
组成（Formulation）
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺（Immunogen）
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Functions as guanine nucleotide exchange factor (GEF) with specificity for RAB11A and RAB25 . Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.
基因名称（Gene Name）
SH3BP5 SAB
蛋白名称
SH3 domain-binding protein 5 (SH3BP-5) (SH3 domain-binding protein that preferentially associates with BTK)
其他名称
=_xlfn.TEXTJOIN(";",TRUE,W3206,X3206,Y3206,Z3206)
细胞定位
Cytoplasmic vesicle membrane ; Peripheral membrane protein . Mitochondrion . Colocalizes with RAB11A on cytoplasmic vesicle membranes. .
组织表达
Highly expressed in testis and ovaries. It is also expressed in a variety of tissues including spleen , lymph node , thymus , bone marrow , fetal liver , colon , small intestine and prostate.
储存（Storage）
-15°C to -25°C/1 year(Do not lower than -25°C)
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