免疫原
Synthesized peptide derived from human ENY2. AA range:1-35
特异性
This antibody detects endogenous levels of ENY2 at Human, Mouse
组成(Formulation)
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺(Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
功能
Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex , participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC , where it is required for transcription. Required for nuclear receptor-mediated transactivation . As a component of the TREX-2 complex , involved in the export of mRNAs to the cytoplasm through the nuclear pores .
蛋白名称
Enhancer of yellow 2 transcription factor homolog
其他名称
=_xlfn.TEXTJOIN(";",TRUE,W3197,X3197,Y3197,Z3197)
细胞定位
Nucleus , nucleoplasm . Localization at the nuclear pore complex requires NUP153 and TPR. .
储存(Storage)
-15°C to -25°C/1 year(Do not lower than -25°C)